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No sex-modulating effects on treatment were detected regardless of therapeutic intervention. They found that desvenlafaxine generally improved depressive symptoms regardless of sex.

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More potential variables include clinical presentation ie, typical versus atypicalantidepressant treatment, differing drugs and dosages, patient adherence to treatment plans, and the type of study conducted prospective or meta-analysis of large data pools. Side effects of antidepressants can also detract Horney chat Mill Valley overall efficacy, particularly if they lead to early discontinuation.

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